Absence of Tissue Inhibitor of Metalloproteinase-4 (TIMP4) ameliorates high fat diet-induced obesity in mice due to defective lipid absorption.

Sakamuri SSVP, Watts R, Takawale A, Wang X, Hernandez-Anzaldo S, Bahitham W, Fernandez-Patron C, Lehner R, Kassiri Z.
Sci Rep. 2017 Jul 24;7(1):6210. doi: 10.1038/s41598-017-05951-4.

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Myocardial overexpression of TIMP3 after myocardial infarction exerts beneficial effects by promoting angiogenesis and suppressing early proteolysis.

Takawale A, Zhang P, Azad A, Wang W, Wang X, Murray AG, Kassiri Z.
Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H224-H236. doi: 10.1152/ajpheart.00108.2017. 

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Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin β1 Interaction.

Takawale A, Zhang P, Patel VB, Wang X, Oudit G, Kassiri Z.
Hypertension. 2017 Jun;69(6):1092-1103. doi: 10.1161/HYPERTENSIONAHA.117.09045. 

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Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase.
van der Veen JN, Lingrell S, Gao X, Takawale A, Kassiri Z, Vance DE, Jacobs RL.
J Lipid Res. 2017 Apr;58(4):656-667. doi: 10.1194/jlr.M070631. 

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Females Are Protected From Iron-Overload Cardiomyopathy Independent of Iron Metabolism: Key Role of Oxidative Stress.
Das SK, Patel VB, Basu R, Wang W, DesAulniers J, Kassiri Z, Oudit GY.
J Am Heart Assoc. 2017 Jan 23;6(1). pii: e003456. doi: 10.1161/JAHA.116.003456.

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Genetic deletion of soluble epoxide hydrolase provides cardioprotective responses following myocardial infarction in aged mice.
Jamieson KL, Samokhvalov V, Akhnokh MK, Lee K, Cho WJ, Takawale A, Wang X, Kassiri Z, Seubert JM.
Prostaglandins Other Lipid Mediat. 2017 Sep;132:47-58. doi: 10.1016/j.prostaglandins.2017.01.001.

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Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage.
Shen M, Morton J, Davidge ST, Kassiri Z.
J Mol Cell Cardiol. 2017 Feb;103:11-21. doi: 10.1016/j.yjmcc.2016.12.001.